Toward an Improved Understanding of Anhedonia

Commentary: Toward an improved understanding of recidivism.

Setting out to identify predictors of recidivism in seriously mentally ill (SMI) persons who return to their community from prison, Hall and colleagues offer to the forensic community a substantive contribution to the organization of interventions aimed to promote both the social and the psychiatric recovery of these individuals and to reduce their rate of re-entry into the penal system. While ...

1 Toward an Improved Understanding of Network Traffic Dynamics

Commentary: toward an improved understanding of administrative segregation.

The questions raised by O'Keefe et al. challenge us to think clearly about the intent of incarceration generally and the objective of administrative segregation in particular. Our comments address several points: the study's methodology, the context of administrative segregation, several attendant pragmatic concerns linked to its practice, and the challenges of understanding the needs and motiv...

Type II diabetes: toward improved understanding and rational therapy.

Still not clearly defined is the fundamental defect or defects involved in the pathogenesis of type II noninsulin-dependent diabetes mellitus. Abnormalities in both insulin secretion and insulin action have been demonstrated, and there has been considerable debate as to which is the predominant lesion. During the 1970s, with the evolution of the concept of two major types of diabetes—type I and...

Toward an Improved Understanding of the Ionizing Radiation Induced DNA Damage/Response Networks in Human Malignancies

1 Departments of Radiation Oncology and Neurological Surgery, Helen Diller Family Comprehensive Cancer Center, UCSF Benioff Children’s Hospital, University of California San Francisco, San Francisco, CA, USA 2 Department of Radiation Oncology, University of California San Francisco, San Francisco, CA, USA 3 Department of Radiation Oncology, Kimmel Cancer Center, Jefferson Medical College, Thoma...